Psychedelic iatrogenic structural dissociation: an exploratory hypothesis on dissociative risks in psychedelic use

This paper introduces the Psychedelic Iatrogenic Structural Dissociation (PISD) hypothesis, proposing that psychedelics may amplify access to dissociated traumatic material, increasing the risk of psychological destabilization in vulnerable individuals. Psychedelics, as “unspecific amplifiers” of mental processes, have the unique ability to bring unresolved trauma into conscious awareness in ways that can be profoundly disruptive